Toshihiro Wajima Selected Research

Cefiderocol

1/2022	Intrapulmonary Pharmacokinetic Modeling and Simulation of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Patients With Pneumonia and Healthy Subjects.
1/2022	Pharmacokinetics, Pharmacodynamics, and Dose Optimization of Cefiderocol during Continuous Renal Replacement Therapy.
10/2021	Intrapulmonary pharmacokinetic profile of cefiderocol in mechanically ventilated patients with pneumonia.
10/2021	Erratum to: Intrapulmonary pharmacokinetic profile of cefiderocol in mechanically ventilated patients with pneumonia.
1/2021	Population Pharmacokinetic and Pharmacokinetic/Pharmacodynamic Analyses of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Patients with Pneumonia, Bloodstream Infection/Sepsis, or Complicated Urinary Tract Infection.
11/2019	Pharmacokinetic and Pharmacodynamic Profiles of Cefiderocol, a Novel Siderophore Cephalosporin.
7/2018	Drug-drug interaction of cefiderocol, a siderophore cephalosporin, via human drug transporters.
1/2018	Population Pharmacokinetic Analysis of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Healthy Subjects, Subjects with Various Degrees of Renal Function, and Patients with Complicated Urinary Tract Infection or Acute Uncomplicated Pyelonephritis.

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Toshihiro Wajima Research Topics

Disease

9	Infections 01/2022 - 01/2012
7	Human Influenza (Influenza) 01/2020 - 01/2012
5	Body Weight (Weight, Body) 11/2019 - 04/2017
4	Pneumonia (Pneumonitis) 01/2022 - 01/2021
3	Critical Illness (Critically Ill) 01/2022 - 10/2021
3	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 12/2020 - 08/2017
2	Healthcare-Associated Pneumonia 10/2021 - 08/2013
2	Thrombocytopenia (Thrombopenia) 01/2021 - 11/2019
2	Liver Diseases (Liver Disease) 01/2021 - 11/2019
2	Urinary Tract Infections (Urinary Tract Infection) 01/2021 - 01/2018
2	Opioid-Induced Constipation 09/2019 - 10/2018
2	HIV Infections (HIV Infection) 10/2014 - 12/2013
1	Sepsis (Septicemia) 01/2021
1	Disease Progression 01/2021
1	Breast Neoplasms (Breast Cancer) 12/2020
1	AIDS-Related Complex (ARC) 11/2019
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 10/2018
1	Cancer Pain 10/2018
1	Neoplasms (Cancer) 10/2018
1	Bacterial Infections (Bacterial Infection) 07/2018
1	Pyelonephritis 01/2018
1	Dyspareunia 05/2015
1	Atrophy 05/2015
1	Exanthema (Rash) 11/2014
1	Nasopharyngitis 11/2014
1	Virus Diseases (Viral Diseases) 01/2012
1	Drug-Related Side Effects and Adverse Reactions 01/2012

Drug/Important Bio-Agent (IBA)

8	CefiderocolIBA 01/2022 - 01/2018
6	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2022 - 01/2018
6	SiderophoresIBA 01/2022 - 01/2018
5	baloxavirIBA 01/2020 - 11/2018
4	Pharmaceutical PreparationsIBA 01/2021 - 11/2014
4	CreatinineIBA 11/2019 - 04/2017
3	lusutrombopagIBA 01/2021 - 11/2019
3	AcidsIBA 01/2020 - 01/2019
2	Carbapenems (Carbapenem Antibiotics)IBA 01/2022 - 11/2019
2	ProdrugsIBA 12/2020 - 01/2020
2	Thrombopoietin ReceptorsIBA 12/2020 - 11/2019
2	Guanfacine (Tenex)FDA LinkGeneric 12/2019 - 08/2017
2	naldemedineIBA 09/2019 - 10/2018
2	Doripenem FDA Link 01/2019 - 08/2013
2	Neuraminidase (Sialidase)IBA 11/2018 - 11/2015
2	peramivirIBA 11/2015 - 01/2012
2	dolutegravirIBA 10/2014 - 12/2013
2	Integrase InhibitorsIBA 10/2014 - 12/2013
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 12/2020
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 12/2020
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 12/2020
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 12/2020
1	Lisdexamfetamine Dimesylate FDA Link 12/2020
1	Proteins (Proteins, Gene)FDA Link 12/2020
1	EndonucleasesIBA 01/2020
1	TabletsIBA 12/2019
1	Narcotic Antagonists (Opioid Antagonists)IBA 09/2019
1	Oseltamivir (Tamiflu)FDA Link 11/2018
1	AlbuminsIBA 04/2017
1	TransferasesIBA 04/2017
1	Alanine (L-Alanine)FDA Link 04/2017
1	BilirubinIBA 04/2017
1	Estrogens (Estrogen)FDA Link 05/2015
1	OspemifeneIBA 05/2015
1	beta-Lactamases (beta-Lactamase)IBA 04/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2013

Therapy/Procedure

2	Artificial Respiration (Mechanical Ventilation) 01/2022 - 01/2021
1	Continuous Renal Replacement Therapy 01/2022
1	Intravenous Infusions 01/2012